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Pharmacokinetics and tolerability of semaglutide in people with hepatic impairment

AIMS: To investigate whether the pharmacokinetic characteristics of semaglutide were altered in people with hepatic impairment, assessed using Child–Pugh criteria, vs those with normal hepatic function. METHODS: In this multicentre, open‐label, parallel‐group trial (sponsor Novo Nordisk, ClinicalTri...

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Detalles Bibliográficos
Autores principales: Jensen, Lene, Kupcova, Viera, Arold, Gerhard, Pettersson, Jonas, Hjerpsted, Julie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873441/
https://www.ncbi.nlm.nih.gov/pubmed/29205786
http://dx.doi.org/10.1111/dom.13186