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The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity

BACKGROUND & AIM: Variations in intestinal microbiota may influence acetaminophen metabolism. This study aimed to determine whether intestinal microbiota are a source of differential susceptibility to acetaminophen-induced hepatotoxicity. METHODS: Conventionally housed C3H/HeH (CH) and C3H/HeH g...

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Detalles Bibliográficos
Autores principales: Possamai, Lucia A, McPhail, Mark JW, Khamri, Wafa, Wu, Bishan, Concas, Danilo, Harrison, Mark, Williams, Roger, Cox, Roger D, Cox, I Jane, Anstee, Quentin M, Thursz, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873516/
https://www.ncbi.nlm.nih.gov/pubmed/25244648
http://dx.doi.org/10.1111/liv.12689