Cargando…
The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity
BACKGROUND & AIM: Variations in intestinal microbiota may influence acetaminophen metabolism. This study aimed to determine whether intestinal microbiota are a source of differential susceptibility to acetaminophen-induced hepatotoxicity. METHODS: Conventionally housed C3H/HeH (CH) and C3H/HeH g...
Autores principales: | Possamai, Lucia A, McPhail, Mark JW, Khamri, Wafa, Wu, Bishan, Concas, Danilo, Harrison, Mark, Williams, Roger, Cox, Roger D, Cox, I Jane, Anstee, Quentin M, Thursz, Mark R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873516/ https://www.ncbi.nlm.nih.gov/pubmed/25244648 http://dx.doi.org/10.1111/liv.12689 |
Ejemplares similares
-
Impact of malnourishment on the pharmacokinetics of acetaminophen and susceptibility to acetaminophen hepatotoxicity
por: Zillen, Daan, et al.
Publicado: (2021) -
Suppressor CD4(+) T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis
por: Khamri, Wafa, et al.
Publicado: (2022) -
Phenylpropionic acid produced by gut microbiota alleviates acetaminophen-induced hepatotoxicity
por: Cho, Sungjoon, et al.
Publicado: (2023) -
PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury
por: Triantafyllou, Evangelos, et al.
Publicado: (2021) -
Mitochondrial–Lysosomal Axis in Acetaminophen Hepatotoxicity
por: Moles, Anna, et al.
Publicado: (2018)