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Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space

The capacity to respond to temperature fluctuations is critical for microorganisms to survive within mammalian hosts, and temperature modulates virulence traits of diverse pathogens. One key temperature-dependent virulence trait of the fungal pathogen Candida albicans is its ability to transition fr...

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Detalles Bibliográficos
Autores principales: Veri, Amanda O., Miao, Zhengqiang, Shapiro, Rebecca S., Tebbji, Faiza, O’Meara, Teresa R., Kim, Sang Hu, Colazo, Juan, Tan, Kaeling, Vyas, Valmik K., Whiteway, Malcolm, Robbins, Nicole, Wong, Koon Ho, Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873724/
https://www.ncbi.nlm.nih.gov/pubmed/29590106
http://dx.doi.org/10.1371/journal.pgen.1007270