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Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space
The capacity to respond to temperature fluctuations is critical for microorganisms to survive within mammalian hosts, and temperature modulates virulence traits of diverse pathogens. One key temperature-dependent virulence trait of the fungal pathogen Candida albicans is its ability to transition fr...
Autores principales: | Veri, Amanda O., Miao, Zhengqiang, Shapiro, Rebecca S., Tebbji, Faiza, O’Meara, Teresa R., Kim, Sang Hu, Colazo, Juan, Tan, Kaeling, Vyas, Valmik K., Whiteway, Malcolm, Robbins, Nicole, Wong, Koon Ho, Cowen, Leah E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873724/ https://www.ncbi.nlm.nih.gov/pubmed/29590106 http://dx.doi.org/10.1371/journal.pgen.1007270 |
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