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Downregulation of miR-374b-5p promotes chemotherapeutic resistance in pancreatic cancer by upregulating multiple anti-apoptotic proteins

Resistance to first-line chemotherapeutic drugs such as gemcitabine contributes to the poor prognosis of patients with pancreatic cancer. MicroRNAs (miRNA) regulate chemoresistance in pancreatic cancer. By analyzing the miRNA sequencing dataset of pancreatic cancer from The Cancer Genome Atlas, it w...

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Detalles Bibliográficos
Autores principales: Sun, Di, Wang, Xu, Sui, Guoqing, Chen, Si, Yu, Miao, Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873836/
https://www.ncbi.nlm.nih.gov/pubmed/29568910
http://dx.doi.org/10.3892/ijo.2018.4315