Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway

Sirtuin 6 (SIRT6) is a member of the nicotinamide adenine dinucleotide positivity-dependent class III deacetylase sirtuin family. The present study aimed to explore the expression and function of SIRT6 in colon cancer. Furthermore, the partial mechanism underlying the dysregulation of SIRT6 was inve...

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Detalles Bibliográficos
Autores principales: Li, Ning, Mao, Dong, Cao, Yansha, Li, Hua, Ren, Fu, Li, Keyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873872/
https://www.ncbi.nlm.nih.gov/pubmed/29512698
http://dx.doi.org/10.3892/ijo.2018.4304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873872/
https://www.ncbi.nlm.nih.gov/pubmed/29512698
http://dx.doi.org/10.3892/ijo.2018.4304

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