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Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF

RAF kinases are major constituents of the mitogen activated signaling pathway, regulating cell proliferation, differentiation and cell survival of many cell types, including neurons. In mammals, the family of RAF proteins consists of three members, ARAF, BRAF, and CRAF. Ablation of CRAF kinase in in...

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Detalles Bibliográficos
Autores principales: Pfeiffer, Verena, Götz, Rudolf, Camarero, Guadelupe, Heinsen, Helmut, Blum, Robert, Rapp, Ulf Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873938/
https://www.ncbi.nlm.nih.gov/pubmed/29590115
http://dx.doi.org/10.1371/journal.pone.0192067