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Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile
BACKGROUND: Sessile serrated polyps (SSPs) have emerged as important precursors for a large number of sporadic colorectal cancers. They are difficult to detect during colonoscopy due to their flat shape and the excessive amounts of secreted mucin that cover the polyps. The underlying genetic and epi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873940/ https://www.ncbi.nlm.nih.gov/pubmed/29590112 http://dx.doi.org/10.1371/journal.pone.0192499 |