Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile

BACKGROUND: Sessile serrated polyps (SSPs) have emerged as important precursors for a large number of sporadic colorectal cancers. They are difficult to detect during colonoscopy due to their flat shape and the excessive amounts of secreted mucin that cover the polyps. The underlying genetic and epi...

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Detalles Bibliográficos
Autores principales: Dehghanizadeh, Somaye, Khoddami, Vahid, Mosbruger, Timothy L., Hammoud, Sue S., Edes, Kornelia, Berry, Therese S., Done, Michelle, Samowitz, Wade S., DiSario, James A., Luba, Daniel G., Burt, Randall W., Jones, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873940/
https://www.ncbi.nlm.nih.gov/pubmed/29590112
http://dx.doi.org/10.1371/journal.pone.0192499

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