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A myeloperoxidase precursor, pro-myeloperoxidase, is present in human plasma and elevated in cardiovascular disease patients

Myeloperoxidase (MPO)-derived oxidants have emerged as a key contributor to tissue damage in inflammatory conditions such as cardiovascular disease. Pro-myeloperoxidase (pro-MPO), an enzymatically active precursor of myeloperoxidase (MPO), is known to be secreted from cultured bone marrow and promye...

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Detalles Bibliográficos
Autores principales: Khalilova, Irada S., Dickerhof, Nina, Mocatta, Tessa J., Bhagra, Catriona J., McClean, Dougal R., Obinger, Christian, Kettle, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873943/
https://www.ncbi.nlm.nih.gov/pubmed/29590135
http://dx.doi.org/10.1371/journal.pone.0192952