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JMJD1A, H3K9me1, H3K9me2 and ADM expression as prognostic markers in oral and oropharyngeal squamous cell carcinoma

AIMS: Jumonji Domain-Containing 1A (JMJD1A) protein promotes demethylation of histones, especially at lysin-9 of di-methylated histone H3 (H3K9me2) or mono-methylated (H3K9me1). Increased levels of H3 histone methylation at lysin-9 (H3K9) is related to tumor suppressor gene silencing. JMJD1A gene ta...

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Detalles Bibliográficos
Autores principales: Maia, Lucas de Lima, Peterle, Gabriela Tonini, dos Santos, Marcelo, Trivilin, Leonardo Oliveira, Mendes, Suzanny Oliveira, de Oliveira, Mayara Mota, dos Santos, Joaquim Gasparini, Stur, Elaine, Agostini, Lidiane Pignaton, Couto, Cinthia Vidal Monteiro da Silva, Dalbó, Juliana, de Assis, Aricia Leone Evangelista Monteiro, Archanjo, Anderson Barros, Mercante, Ana Maria Da Cunha, Lopez, Rossana Veronica Mendoza, Nunes, Fábio Daumas, de Carvalho, Marcos Brasilino, Tajara, Eloiza Helena, Louro, Iúri Drumond, Álvares-da-Silva, Adriana Madeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874045/
https://www.ncbi.nlm.nih.gov/pubmed/29590186
http://dx.doi.org/10.1371/journal.pone.0194884