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Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis
Understanding the regulation of insulin biosynthesis is important as it plays a central role in glucose metabolism. The mouse insulin gene2 (Ins2) has two splice variants; long (Ins2L) and short (Ins2S), that differ only in their 5’UTR sequence and Ins2S is the major transcript which translate more...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874046/ https://www.ncbi.nlm.nih.gov/pubmed/29590218 http://dx.doi.org/10.1371/journal.pone.0194482 |