A fatty acid analogue targeting mitochondria exerts a plasma triacylglycerol lowering effect in rats with impaired carnitine biosynthesis

L-carnitine is important for the catabolism of long-chain fatty acids in the mitochondria. We investigated how the triacylglycerol (TAG)-lowering drug 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA) influenced lipid metabolism in carnitine-depleted, 3-(2,2,2-trimethylhydrazinium)propionate dehyd...

Descripción completa

Detalles Bibliográficos
Autores principales: Lindquist, Carine, Bjørndal, Bodil, Rossmann, Christine Renate, Svardal, Asbjørn, Hallström, Seth, Berge, Rolf Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874065/
https://www.ncbi.nlm.nih.gov/pubmed/29590220
http://dx.doi.org/10.1371/journal.pone.0194978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874065/
https://www.ncbi.nlm.nih.gov/pubmed/29590220
http://dx.doi.org/10.1371/journal.pone.0194978

Ejemplares similares