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BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex

Protein trafficking within cilia is mediated by the intraflagellar transport (IFT) machinery composed of large protein complexes. The BBSome consists of eight BBS proteins encoded by causative genes of Bardet-Biedl syndrome (BBS), and has been implicated in the trafficking of ciliary membrane protei...

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Detalles Bibliográficos
Autores principales: Nozaki, Shohei, Katoh, Yohei, Kobayashi, Takuya, Nakayama, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874067/
https://www.ncbi.nlm.nih.gov/pubmed/29590217
http://dx.doi.org/10.1371/journal.pone.0195005