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The exclusive effects of chaperonin on the behavior of proteins with 5(2) knot
The folding of proteins with a complex knot is still an unresolved question. Based on representative members of Ubiquitin C-terminal Hydrolases (UCHs) that contain the 5(2) knot in the native state, we explain how UCHs are able to unfold and refold in vitro reversibly within the structure-based mode...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874080/ https://www.ncbi.nlm.nih.gov/pubmed/29547629 http://dx.doi.org/10.1371/journal.pcbi.1005970 |