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Combined Effects of Baicalein and Docetaxel on Apoptosis in 8505c Anaplastic Thyroid Cancer Cells via Downregulation of the ERK and Akt/mTOR Pathways

BACKGROUND: Anaplastic thyroid cancer (ATC) is one of the most lethal human malignancies. Docetaxel, a microtubule stabilizer, is a common chemotherapeutic agent used to treat various metastatic cancers. However, prolonged use results in various side effects and drug resistance. Flavonoids, such as...

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Detalles Bibliográficos
Autores principales: Park, Chan Ho, Han, Se Eun, Nam-Goong, Il Seong, Kim, Young Il, Kim, Eun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874188/
https://www.ncbi.nlm.nih.gov/pubmed/29589394
http://dx.doi.org/10.3803/EnM.2018.33.1.121