Cargando…

Combined Effects of Baicalein and Docetaxel on Apoptosis in 8505c Anaplastic Thyroid Cancer Cells via Downregulation of the ERK and Akt/mTOR Pathways

BACKGROUND: Anaplastic thyroid cancer (ATC) is one of the most lethal human malignancies. Docetaxel, a microtubule stabilizer, is a common chemotherapeutic agent used to treat various metastatic cancers. However, prolonged use results in various side effects and drug resistance. Flavonoids, such as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Chan Ho, Han, Se Eun, Nam-Goong, Il Seong, Kim, Young Il, Kim, Eun Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Endocrine Society 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874188/ https://www.ncbi.nlm.nih.gov/pubmed/29589394 http://dx.doi.org/10.3803/EnM.2018.33.1.121

Ejemplares similares

Curcumin Enhances Docetaxel-Induced Apoptosis of 8505C Anaplastic Thyroid Carcinoma Cells
por: Hong, Jung Min, et al.
Publicado: (2014)

Ouabain Effects on Human Anaplastic Thyroid Carcinoma 8505C Cells
por: Teixeira, Mariana Pires, et al.
Publicado: (2022)

Downregulation of AKT/mTOR signaling pathway for Salmonella-mediated autophagy in human anaplastic thyroid cancer
por: Wu, Li-Hsien, et al.
Publicado: (2022)

Berberine Inhibited the Growth of Thyroid Cancer Cell Lines 8505C and TPC1
por: Park, Kyoung Sik, et al.
Publicado: (2012)

Baicalein inhibits prostate cancer cell growth and metastasis via the caveolin-1/AKT/mTOR pathway
por: Guo, Zhaoxin, et al.
Publicado: (2015)

Downregulation of PI3K/AKT/mTOR Pathway in Juglone-Treated Bovine Oocytes
por: El-Sheikh, Marwa, et al.
Publicado: (2023)

Targeting XPO1 and PAK4 in 8505C Anaplastic Thyroid Cancer Cells: Putative Implications for Overcoming Lenvatinib Therapy Resistance
por: Khan, Husain Yar, et al.
Publicado: (2019)

Baicalein Induces Apoptosis of Rheumatoid Arthritis Synovial Fibroblasts through Inactivation of the PI3K/Akt/mTOR Pathway
por: Zhang, Xue, et al.
Publicado: (2022)

Roles of Akt and ERK in mTOR-Dependent Antidepressant Effects of Vanillic Acid
por: Chuang, Han-Wen, et al.
Publicado: (2020)

Apatinib-induced protective autophagy and apoptosis through the AKT–mTOR pathway in anaplastic thyroid cancer
por: Feng, Haoran, et al.
Publicado: (2018)

C-Reactive Protein Inhibits Survivin Expression via Akt/mTOR Pathway Downregulation by PTEN Expression in Cardiac Myocytes
por: Lee, Beom Seob, et al.
Publicado: (2014)

Inhibition of DNMT3B and PI3K/AKT/mTOR and ERK Pathways as a Novel Mechanism of Volasertib on Hypomethylating Agent-Resistant Cells
por: Choi, Eun-Ji, et al.
Publicado: (2023)

Papillary thyroid cancer with Hashimoto’s thyroiditis attenuates the tumour aggressiveness through the up-regulation of E-cadherin and TGF-β expression
por: Kim, Su Jin, et al.
Publicado: (2022)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Regulates Neurite Outgrowth Through the Activation of Akt/mTOR and Erk/mTOR Signaling Pathways
por: Wen, Wen, et al.
Publicado: (2020)

Effects of Rosiglitazone on Inflammation in Otsuka Long-Evans Tokushima Fatty Rats
por: Lee, Jin Woo, et al.
Publicado: (2010)

Oncogenic Ras is downregulated by ARHI and induces autophagy by Ras/AKT/mTOR pathway in glioblastoma
por: Zhong, Chen, et al.
Publicado: (2019)

Hedyotis diffusa Willd. Suppresses Hepatocellular Carcinoma via Downregulating AKT/mTOR Pathways
por: Huang, Lingli, et al.
Publicado: (2021)

The Paradox of Akt-mTOR Interactions
por: Vadlakonda, Lakshmipathi, et al.
Publicado: (2013)

The Programming of Cardiac Hypertrophy in the Offspring by Maternal Obesity Is Associated with Hyperinsulinemia, AKT, ERK, and mTOR Activation
por: Fernandez-Twinn, Denise S., et al.
Publicado: (2012)

The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas
por: Du, Juan, et al.
Publicado: (2016)

Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer
por: Rai, Rajani, et al.
Publicado: (2020)

Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy
por: Li, Qingfang, et al.
Publicado: (2022)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Downregulation of BZW2 inhibits osteosarcoma cell growth by inactivating the Akt/mTOR signaling pathway
por: Cheng, Dong-Dong, et al.
Publicado: (2017)

GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells
por: Xu, Hao, et al.
Publicado: (2019)

PI3K/AKT/mTOR Signaling Pathway Is Downregulated by Runzaoling (RZL) in Sjögren's Syndrome
por: Zeng, Ping, et al.
Publicado: (2022)

Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma
por: Sun, Eun Jin, et al.
Publicado: (2021)

Thrombin Generation Assay Detects Moderate-Intensity Statin-Induced Reduction of Hypercoagulability in Diabetes
por: Park, Hee Sue, et al.
Publicado: (2018)

A Case of Cavernous Sinus Thrombophlebitis and Meningitis as a Complication in Osteopetrosis
por: Chung, Hyun Chul, et al.
Publicado: (2014)

Epigenetic downregulation of STAT6 increases HIF-1α expression via mTOR/S6K/S6, leading to enhanced hypoxic viability of glioma cells
por: Park, Soo Jung, et al.
Publicado: (2019)

Algae Undaria pinnatifida Protects Hypothalamic Neurons against Endoplasmic Reticulum Stress through Akt/mTOR Signaling
por: Kim, Jongwan, et al.
Publicado: (2015)

C-C motif chemokine ligand 2 promotes myogenesis of myoblasts via the AKT-mTOR pathway
por: Kwak, Mi Kyung, et al.
Publicado: (2022)

Endothelial Cells Promote Docetaxel Resistance of Prostate Cancer Cells by Inducing ERG Expression and Activating Akt/mTOR Signaling Pathway
por: Zhou, Wenhao, et al.
Publicado: (2020)

Aromadendrin Protects Neuronal Cells from Methamphetamine-Induced Neurotoxicity by Regulating Endoplasmic Reticulum Stress and PI3K/Akt/mTOR Signaling Pathway
por: Lee, Hyun-Su, et al.
Publicado: (2021)

Synergistic Effects of Combination Therapy with AKT and mTOR Inhibitors on Bladder Cancer Cells
por: Kim, Hyera, et al.
Publicado: (2020)

Orf virus induces complete autophagy to promote viral replication via inhibition of AKT/mTOR and activation of the ERK1/2/mTOR signalling pathway in OFTu cells
por: Lv, Lijun, et al.
Publicado: (2023)

Dyskerin Downregulation Can Induce ER Stress and Promote Autophagy via AKT-mTOR Signaling Deregulation
por: Maiello, Daniela, et al.
Publicado: (2022)

Knockdown of TFRC suppressed the progression of nasopharyngeal carcinoma by downregulating the PI3K/Akt/mTOR pathway
por: Feng, Guofei, et al.
Publicado: (2023)

Chrysin Induces Apoptosis via the MAPK Pathway and Regulates ERK/mTOR-Mediated Autophagy in MC-3 Cells
por: Jung, Gi-Hwan, et al.
Publicado: (2022)

mTOR Activation by PI3K/Akt and ERK Signaling in Short ELF-EMF Exposed Human Keratinocytes
por: Patruno, Antonia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8qog755qbg3h1qoi7422279lp6