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Validation of [(18)F]FLT as a perfusion-independent imaging biomarker of tumour response in EGFR-mutated NSCLC patients undergoing treatment with an EGFR tyrosine kinase inhibitor
BACKGROUND: 3′-Deoxy-3′-[(18)F]fluorothymidine ([(18)F]FLT) was proposed as an imaging biomarker for the assessment of in vivo cellular proliferation with positron emission tomography (PET). The current study aimed to validate [(18)F]FLT as a perfusion-independent PET tracer, by gaining insight in t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874225/ https://www.ncbi.nlm.nih.gov/pubmed/29594931 http://dx.doi.org/10.1186/s13550-018-0376-6 |