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Validation of [(18)F]FLT as a perfusion-independent imaging biomarker of tumour response in EGFR-mutated NSCLC patients undergoing treatment with an EGFR tyrosine kinase inhibitor

BACKGROUND: 3′-Deoxy-3′-[(18)F]fluorothymidine ([(18)F]FLT) was proposed as an imaging biomarker for the assessment of in vivo cellular proliferation with positron emission tomography (PET). The current study aimed to validate [(18)F]FLT as a perfusion-independent PET tracer, by gaining insight in t...

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Detalles Bibliográficos
Autores principales:	Iqbal, R., Kramer, G. M., Frings, V., Smit, E. F., Hoekstra, O. S., Boellaard, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874225/ https://www.ncbi.nlm.nih.gov/pubmed/29594931 http://dx.doi.org/10.1186/s13550-018-0376-6

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