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Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E(2) synthetic pathway

Hyperproduced prostaglandin E(2) by cyclooxygenase-2 and microsomal prostaglandin E synthase-1 evokes several pathophysiological responses such as inflammation and carcinogenesis. Our recent study demonstrated that Dioscorea japonica extract suppressed the expression of cyclooxygenase-2 and microsom...

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Detalles Bibliográficos
Autores principales: Tsukayama, Izumi, Toda, Keisuke, Takeda, Yasunori, Mega, Takuto, Tanaka, Mitsuki, Kawakami, Yuki, Takahashi, Yoshitaka, Kimoto, Masumi, Yamamoto, Kei, Miki, Yoshimi, Murakami, Makoto, Suzuki-Yamamoto, Toshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874233/
https://www.ncbi.nlm.nih.gov/pubmed/29610553
http://dx.doi.org/10.3164/jcbn.17-54