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SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion

The EMT inducer SNAIL1 regulates breast cancer metastasis and its expression in human primary breast tumor predicts for poor outcomes. During tumor progression SNAIL1 has multiple effects in tumor cells that can impact metastasis. An inflammatory tumor microenvironment also impacts metastasis and re...

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Detalles Bibliográficos
Autores principales: Brenot, Audrey, Knolhoff, Brett L., DeNardo, David G., Longmore, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874242/
https://www.ncbi.nlm.nih.gov/pubmed/29593211
http://dx.doi.org/10.1038/s41389-018-0042-x