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SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion
The EMT inducer SNAIL1 regulates breast cancer metastasis and its expression in human primary breast tumor predicts for poor outcomes. During tumor progression SNAIL1 has multiple effects in tumor cells that can impact metastasis. An inflammatory tumor microenvironment also impacts metastasis and re...
Autores principales: | Brenot, Audrey, Knolhoff, Brett L., DeNardo, David G., Longmore, Gregory D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874242/ https://www.ncbi.nlm.nih.gov/pubmed/29593211 http://dx.doi.org/10.1038/s41389-018-0042-x |
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