Cargando…

CHIP regulates bone mass by targeting multiple TRAF family members in bone marrow stromal cells

Carboxyl terminus of Hsp70-interacting protein (CHIP or STUB1) is an E3 ligase and regulates the stability of several proteins which are involved in different cellular functions. Our previous studies demonstrated that Chip deficient mice display bone loss phenotype due to increased osteoclast format...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tingyu, Li, Shan, Yi, Dan, Zhou, Guang-Qian, Chang, Zhijie, Ma, Peter X., Xiao, Guozhi, Chen, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874245/
https://www.ncbi.nlm.nih.gov/pubmed/29619270
http://dx.doi.org/10.1038/s41413-018-0010-2