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CHIP regulates bone mass by targeting multiple TRAF family members in bone marrow stromal cells
Carboxyl terminus of Hsp70-interacting protein (CHIP or STUB1) is an E3 ligase and regulates the stability of several proteins which are involved in different cellular functions. Our previous studies demonstrated that Chip deficient mice display bone loss phenotype due to increased osteoclast format...
Autores principales: | Wang, Tingyu, Li, Shan, Yi, Dan, Zhou, Guang-Qian, Chang, Zhijie, Ma, Peter X., Xiao, Guozhi, Chen, Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874245/ https://www.ncbi.nlm.nih.gov/pubmed/29619270 http://dx.doi.org/10.1038/s41413-018-0010-2 |
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