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Hypersensitivity of Prelimbic Cortex Neurons Contributes to Aggravated Nociceptive Responses in Rats With Experience of Chronic Inflammatory Pain

Previous experience of chronic pain causes enhanced responses to upcoming noxious events in both humans and animals, but the underlying mechanisms remain unclear. In the present study, we found that rats with complete Freund’s adjuvant (CFA)-induced chronic inflammatory pain experience exhibited agg...

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Detalles Bibliográficos
Autores principales: Fan, Xiao-Cen, Fu, Su, Liu, Feng-Yu, Cui, Shuang, Yi, Ming, Wan, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874315/
https://www.ncbi.nlm.nih.gov/pubmed/29623029
http://dx.doi.org/10.3389/fnmol.2018.00085