Immunogenicity in Rabbits of HIV-1 SOSIP Trimers from Clades A, B, and C, Given Individually, Sequentially, or in Combination

Recombinant soluble HIV-1 envelope glycoprotein (Env) SOSIP trimers are a design platform for inducing broadly neutralizing antibodies (bNAbs) by vaccination. To date, these and alternative designs of native-like trimers, given singly or in pairs, have not induced bNAbs in test animals such as rabbi...

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Detalles Bibliográficos
Autores principales: Torrents de la Peña, Alba, de Taeye, Steven W., Sliepen, Kwinten, LaBranche, Celia C., Burger, Judith A., Schermer, Edith E., Montefiori, David C., Moore, John P., Klasse, Per Johan, Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874403/
https://www.ncbi.nlm.nih.gov/pubmed/29367243
http://dx.doi.org/10.1128/JVI.01957-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874403/
https://www.ncbi.nlm.nih.gov/pubmed/29367243
http://dx.doi.org/10.1128/JVI.01957-17

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