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Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP(5+), Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation

Radiation injury to the lung is the result of acute and chronic free radical formation, and there are currently few effective means of mitigating such injury. Studies in rodents indicate that superoxide dismutase mimetics may be effective in this regard; however, studies in humans or large animals a...

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Detalles Bibliográficos
Autores principales: Cline, John Mark, Dugan, Greg, Bourland, John Daniel, Perry, Donna L., Stitzel, Joel D., Weaver, Ashley A., Jiang, Chen, Tovmasyan, Artak, Owzar, Kouros, Spasojevic, Ivan, Batinic-Haberle, Ines, Vujaskovic, Zeljko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874526/
https://www.ncbi.nlm.nih.gov/pubmed/29518913
http://dx.doi.org/10.3390/antiox7030040