Redistribution of Extracellular Superoxide Dismutase Causes Neonatal Pulmonary Vascular Remodeling and PH but Protects Against Experimental Bronchopulmonary Dysplasia

Background: A naturally occurring single nucleotide polymorphism (SNP), (R(213)G), in extracellular superoxide dismutase (SOD3), decreases SOD3 matrix binding affinity. Humans and mature mice expressing the R(213)G SNP exhibit increased cardiovascular disease but decreased lung disease. The impact o...

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Detalles Bibliográficos
Autores principales: Sherlock, Laurie G., Trumpie, Ashley, Hernandez-Lagunas, Laura, McKenna, Sarah, Fisher, Susan, Bowler, Russell, Wright, Clyde J., Delaney, Cassidy, Nozik-Grayck, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874528/
https://www.ncbi.nlm.nih.gov/pubmed/29538340
http://dx.doi.org/10.3390/antiox7030042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874528/
https://www.ncbi.nlm.nih.gov/pubmed/29538340
http://dx.doi.org/10.3390/antiox7030042

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