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Immunogenicity in African Green Monkeys of M Protein Mutant Vesicular Stomatitis Virus Vectors and Contribution of Vector-Encoded Flagellin

Recombinant vesicular stomatitis virus (VSV) is a promising platform for vaccine development. M51R VSV, an attenuated, M protein mutant strain, is an effective inducer of Type I interferon and dendritic cell (DC) maturation, which are desirable properties to exploit for vaccine design. We have previ...

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Detalles Bibliográficos
Autores principales: Westcott, Marlena M., Smedberg, Jason, Jorgensen, Matthew J., Puckett, Shelby, Lyles, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874657/
https://www.ncbi.nlm.nih.gov/pubmed/29562688
http://dx.doi.org/10.3390/vaccines6010016