BET Family Protein BRD4: An Emerging Actor in NFκB Signaling in Inflammation and Cancer

NFκB (Nuclear Factor-κ-light-chain-enhancer of activated B cells) signaling elicits global transcriptional changes by activating cognate promoters and through genome-wide remodeling of cognate regulatory elements called “super enhancers”. BET (Bromodomain and Extra-Terminal domain) protein family in...

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Detalles Bibliográficos
Autores principales: Hajmirza, Azadeh, Emadali, Anouk, Gauthier, Arnaud, Casasnovas, Olivier, Gressin, Rémy, Callanan, Mary B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874673/
https://www.ncbi.nlm.nih.gov/pubmed/29415456
http://dx.doi.org/10.3390/biomedicines6010016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874673/
https://www.ncbi.nlm.nih.gov/pubmed/29415456
http://dx.doi.org/10.3390/biomedicines6010016

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