Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation

Bryonolic acid (BrA) is a pentacyclic triterpene present in several plants used in African traditional medicine such as Anisophyllea dichostyla R. Br. Here we investigated the in vitro anticancer properties of BrA. We report that BrA inhibits acyl-coA: cholesterol acyl transferase (ACAT) activity in...

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Detalles Bibliográficos
Autores principales: Khallouki, Farid, Owen, Robert Wyn, Silvente-Poirot, Sandrine, Poirot, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874678/
https://www.ncbi.nlm.nih.gov/pubmed/29439506
http://dx.doi.org/10.3390/biomedicines6010021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874678/
https://www.ncbi.nlm.nih.gov/pubmed/29439506
http://dx.doi.org/10.3390/biomedicines6010021

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