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Heterodimer Binding Scaffolds Recognition via the Analysis of Kinetically Hot Residues

Physical interactions between proteins are often difficult to decipher. The aim of this paper is to present an algorithm that is designed to recognize binding patches and supporting structural scaffolds of interacting heterodimer proteins using the Gaussian Network Model (GNM). The recognition is ba...

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Detalles Bibliográficos
Autor principal: Perišić, Ognjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874725/
https://www.ncbi.nlm.nih.gov/pubmed/29547506
http://dx.doi.org/10.3390/ph11010029