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Heterodimer Binding Scaffolds Recognition via the Analysis of Kinetically Hot Residues
Physical interactions between proteins are often difficult to decipher. The aim of this paper is to present an algorithm that is designed to recognize binding patches and supporting structural scaffolds of interacting heterodimer proteins using the Gaussian Network Model (GNM). The recognition is ba...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874725/ https://www.ncbi.nlm.nih.gov/pubmed/29547506 http://dx.doi.org/10.3390/ph11010029 |