Cargando…

The Evolutionary unZIPping of a Dimerization Motif—A Comparison of ZIP and PrP Architectures

The cellular prion protein, notorious for its causative role in a range of fatal neurodegenerative diseases, evolved from a Zrt-/Irt-like Protein (ZIP) zinc transporter approximately 500 million years ago. Whilst atomic structures for recombinant prion protein (PrP) from various species have been av...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Jian, Wille, Holger, Schmitt-Ulms, Gerold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874730/ http://dx.doi.org/10.3390/pathogens7010004

Ejemplares similares

The ZIP5 Ectodomain Co-Localizes with PrP and May Acquire a PrP-Like Fold That Assembles into a Dimer
por: Pocanschi, Cosmin L., et al.
Publicado: (2013)

Evolutionary Descent of Prion Genes from the ZIP Family of Metal Ion Transporters
por: Schmitt-Ulms, Gerold, et al.
Publicado: (2009)

Zipping and Unzipping of Cosmic String Loops in Collision
por: Firouzjahi, Hassan, et al.
Publicado: (2009)

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration
por: Taylor, Kathryn M., et al.
Publicado: (2016)

A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition
por: Brethour, Dylan, et al.
Publicado: (2017)

Molecular ZIP codes in targeted drug delivery
por: Ruoslahti, Erkki
Publicado: (2022)

The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018)

ZIP Code and GIS Studies: Kouznetsova et al. Respond
por: Kouznetsova, Maria, et al.
Publicado: (2008)

Using ZIP Code and GIS Studies to Assess Disease Risk
por: Golden, Robert, et al.
Publicado: (2008)

Localization of ZIP14 and ZIP8 in HIBCPP Cells
por: Morgan, Shannon E., et al.
Publicado: (2020)

Heterogeneous Immunolocalisation of Zinc Transporters ZIP6, ZIP10 and ZIP14 in Human Normo- and Asthenozoospermic Spermatozoa
por: Protic, Isidora, et al.
Publicado: (2022)

Systematic evolution of bZIP transcription factors in Malvales and functional exploration of AsbZIP14 and AsbZIP41 in Aquilaria sinensis
por: Zhang, Hao, et al.
Publicado: (2023)

Regulation of PrP(C) signaling and processing by dimerization
por: Roucou, Xavier
Publicado: (2014)

Uncharacterized conserved motifs outside the HD-Zip domain in HD-Zip subfamily I transcription factors; a potential source of functional diversity
por: Arce, Agustín L, et al.
Publicado: (2011)

Iomega ZIP 250
Publicado: (2017)

The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis
por: Nimmanon, Thirayost, et al.
Publicado: (2020)

A-ZIP53, a dominant negative reveals the molecular mechanism of heterodimerization between bZIP53, bZIP10 and bZIP25 involved in Arabidopsis seed maturation
por: Jain, Prateek, et al.
Publicado: (2017)

Reduction/oxidation-phosphorylation control of DNA binding in the bZIP dimerization network
por: Amoutzias, Gregory D, et al.
Publicado: (2006)

Combinatorial bZIP dimers display complex DNA-binding specificity landscapes
por: Rodríguez-Martínez, José A, et al.
Publicado: (2017)

New Frontiers for the NFIL3 bZIP Transcription Factor in Cancer, Metabolism and Beyond
por: Keniry, Megan, et al.
Publicado: (2014)

Shared nucleotide flanks confer transcriptional competency to bZip core motifs
por: Cohen, Daniel M, et al.
Publicado: (2018)

Iron uptake by ZIP8 and ZIP14 in human proximal tubular epithelial cells
por: van Raaij, S. E. G., et al.
Publicado: (2019)

Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14
por: Scheiber, Ivo F., et al.
Publicado: (2019)

The Functions of ZIP8, ZIP14, and ZnT10 in the Regulation of Systemic Manganese Homeostasis
por: Winslow, James W.W., et al.
Publicado: (2020)

Zip it up to shut it down
por: Zhu, Xuan, et al.
Publicado: (2014)

On the use of ZIP codes and ZIP code tabulation areas (ZCTAs) for the spatial analysis of epidemiological data
por: Grubesic, Tony H, et al.
Publicado: (2006)

Different Actions of Intracellular Zinc Transporters ZIP7 and ZIP13 Are Essential for Dermal Development
por: Lee, Mi-Gi, et al.
Publicado: (2019)

The bZIP transcription factor TabZIP15 improves salt stress tolerance in wheat
por: Bi, Chenxi, et al.
Publicado: (2020)

The bZIP Transcription Factor ZIP-11 Is Required for the Innate Immune Regulation in Caenorhabditis elegans
por: Zheng, Zhongfan, et al.
Publicado: (2021)

Genome-wide identification and evolutionary analyses of bZIP transcription factors in wheat and its relatives and expression profiles of anther development related TabZIP genes
por: Li, Xueyin, et al.
Publicado: (2015)

Zip! tips: ZIPs for Outlook, iPad, iPhone, Gmail, Google, and much, much more!
por: Song, Mike, et al.
Publicado: (2013)

The prion 2018 round tables (I): the structure of PrP(Sc)
por: Baskakov, Ilia V., et al.
Publicado: (2019)

The Soybean bZIP Transcription Factor Gene GmbZIP2 Confers Drought and Salt Resistances in Transgenic Plants
por: Yang, Yan, et al.
Publicado: (2020)

Somatostatin in Alzheimer's disease: A new Role for an Old Player
por: Solarski, Michael, et al.
Publicado: (2018)

Two Cassava Basic Leucine Zipper (bZIP) Transcription Factors (MebZIP3 and MebZIP5) Confer Disease Resistance against Cassava Bacterial Blight
por: Li, Xiaolin, et al.
Publicado: (2017)

Computer Security: “New_invoice.zip”
por: Stefan Lueders, Computer Security Team
Publicado: (2015)

With PIPs, you get ZIPs and blips
por: Senning, Eric N.
Publicado: (2019)

The bZIP Proteins of Oncogenic Viruses
por: Stolz, Madeleine L., et al.
Publicado: (2020)

hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands
por: Desouki, Mohamed M, et al.
Publicado: (2007)

Functional Analysis of NtZIP4B and Zn Status-Dependent Expression Pattern of Tobacco ZIP Genes
por: Barabasz, Anna, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lfu87aqia3d66veq0tio8k8p7q