Pharmacological Agents Targeting the Cellular Prion Protein

Prion diseases are associated with the conversion of the cellular prion protein (PrP(C)), a glycoprotein expressed at the surface of a wide variety of cell types, into a misfolded conformer (the scrapie form of PrP, or PrP(Sc)) that accumulates in brain tissues of affected individuals. PrP(Sc) is a...

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Detalles Bibliográficos
Autores principales: Barreca, Maria Letizia, Iraci, Nunzio, Biggi, Silvia, Cecchetti, Violetta, Biasini, Emiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874753/
https://www.ncbi.nlm.nih.gov/pubmed/29518975
http://dx.doi.org/10.3390/pathogens7010027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874753/
https://www.ncbi.nlm.nih.gov/pubmed/29518975
http://dx.doi.org/10.3390/pathogens7010027

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