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Preventing Crystal Agglomeration of Pharmaceutical Crystals Using Temperature Cycling and a Novel Membrane Crystallization Procedure for Seed Crystal Generation

In this work, a novel membrane crystallization system was used to crystallize micro-sized seeds of piroxicam monohydrate by reverse antisolvent addition. Membrane crystallization seeds were compared with seeds produced by conventional antisolvent addition and polymorphic transformation of a fine pow...

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Detalles Bibliográficos
Autores principales: Simone, Elena, Othman, Rahimah, Vladisavljević, Goran T., Nagy, Zoltan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874830/
https://www.ncbi.nlm.nih.gov/pubmed/29364167
http://dx.doi.org/10.3390/pharmaceutics10010017