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Epinephrine in Anaphylaxis: Preclinical Study of Pharmacokinetics after Sublingual Administration of Taste-Masked Tablets for Potential Pediatric Use

Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to fatalities—especially in children. A novel rapidly-disintegrating sublingual tablet (RDS...

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Detalles Bibliográficos
Autores principales: Rachid, Ousama, Rawas-Qalaji, Mutasem, Simons, Keith J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874837/
https://www.ncbi.nlm.nih.gov/pubmed/29439456
http://dx.doi.org/10.3390/pharmaceutics10010024