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Rational Design, Synthesis and Evaluation of γ-CD-Containing Cross-Linked Polyvinyl Alcohol Hydrogel as a Prednisone Delivery Platform

This study describes the in-silico rational design, synthesis and evaluation of cross-linked polyvinyl alcohol hydrogels containing γ-cyclodextrin (γ-CDHSAs) as platforms for the sustained release of prednisone (PDN). Through in-silico studies using semi-empirical quantum mechanical calculations, th...

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Detalles Bibliográficos
Autores principales: Marican, Adolfo, Avila-Salas, Fabián, Valdés, Oscar, Wehinger, Sergio, Villaseñor, Jorge, Fuentealba, Natalia, Arenas-Salinas, Mauricio, Argandoña, Yerko, Carrasco-Sánchez, Verónica, Durán-Lara, Esteban F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874843/
https://www.ncbi.nlm.nih.gov/pubmed/29518980
http://dx.doi.org/10.3390/pharmaceutics10010030