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Effect of Pyruvate Decarboxylase Knockout on Product Distribution Using Pichia pastoris (Komagataella phaffii) Engineered for Lactic Acid Production

Lactic acid is the monomer unit of the bioplastic poly-lactic acid (PLA). One candidate organism for lactic acid production is Pichia pastoris, a yeast widely used for heterologous protein production. Nevertheless, this yeast has a poor fermentative capability that can be modulated by controlling ox...

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Detalles Bibliográficos
Autores principales: Melo, Nadiele T. M., Mulder, Kelly C. L., Nicola, André Moraes, Carvalho, Lucas S., Menino, Gisele S., Mulinari, Eduardo, Parachin, Nádia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874883/
https://www.ncbi.nlm.nih.gov/pubmed/29462904
http://dx.doi.org/10.3390/bioengineering5010017