The Typhoid Toxin Produced by the Nontyphoidal Salmonella enterica Serotype Javiana Is Required for Induction of a DNA Damage Response In Vitro and Systemic Spread In Vivo

The Salmonella cytolethal distending toxin (S-CDT), first described as the “typhoid toxin” in Salmonella enterica subsp. enterica serotype Typhi, induces DNA damage in eukaryotic cells. Recent studies have shown that more than 40 nontyphoidal Salmonella (NTS) serotypes carry genes that encode S-CDT,...

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Detalles Bibliográficos
Autores principales: Miller, Rachel A., Betteken, Michael I., Guo, Xiaodong, Altier, Craig, Duhamel, Gerald E., Wiedmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874915/
https://www.ncbi.nlm.nih.gov/pubmed/29588404
http://dx.doi.org/10.1128/mBio.00467-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874915/
https://www.ncbi.nlm.nih.gov/pubmed/29588404
http://dx.doi.org/10.1128/mBio.00467-18

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