Exogenous Stimulation of Type I Interferon Protects Mice with Chronic Granulomatous Disease from Aspergillosis through Early Recruitment of Host-Protective Neutrophils into the Lung

Invasive aspergillosis (IA) remains the primary cause of morbidity and mortality in chronic granulomatous disease (CGD) patients, often due to infection by Aspergillus species refractory to antifungals. This motivates the search for alternative treatments, including immunotherapy. We investigated th...

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Detalles Bibliográficos
Autores principales: Seyedmousavi, Seyedmojtaba, Davis, Michael J., Sugui, Janyce A., Pinkhasov, Tzvia, Moyer, Shannon, Salazar, Andres M., Chang, Yun C., Kwon-Chung, Kyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874922/
https://www.ncbi.nlm.nih.gov/pubmed/29588403
http://dx.doi.org/10.1128/mBio.00422-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874922/
https://www.ncbi.nlm.nih.gov/pubmed/29588403
http://dx.doi.org/10.1128/mBio.00422-18

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