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Exogenous Stimulation of Type I Interferon Protects Mice with Chronic Granulomatous Disease from Aspergillosis through Early Recruitment of Host-Protective Neutrophils into the Lung
Invasive aspergillosis (IA) remains the primary cause of morbidity and mortality in chronic granulomatous disease (CGD) patients, often due to infection by Aspergillus species refractory to antifungals. This motivates the search for alternative treatments, including immunotherapy. We investigated th...
Autores principales: | Seyedmousavi, Seyedmojtaba, Davis, Michael J., Sugui, Janyce A., Pinkhasov, Tzvia, Moyer, Shannon, Salazar, Andres M., Chang, Yun C., Kwon-Chung, Kyung J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874922/ https://www.ncbi.nlm.nih.gov/pubmed/29588403 http://dx.doi.org/10.1128/mBio.00422-18 |
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