Autoantibodies in Serum of Systemic Scleroderma Patients: Peptide-Based Epitope Mapping Indicates Increased Binding to Cytoplasmic Domains of CXCR3

Systemic sclerosis (SSc) is a severe chronic autoimmune disease with high morbidity and mortality. Sera of patients with SSc contain a large variety of autoantibody (aab) reactivities. Among these are functionally active aab that bind to G protein-coupled receptors (GPCR) such as C-X-C motif chemoki...

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Detalles Bibliográficos
Autores principales: Recke, Andreas, Regensburger, Ann-Katrin, Weigold, Florian, Müller, Antje, Heidecke, Harald, Marschner, Gabriele, Hammers, Christoph M., Ludwig, Ralf J., Riemekasten, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874968/
https://www.ncbi.nlm.nih.gov/pubmed/29623076
http://dx.doi.org/10.3389/fimmu.2018.00428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874968/
https://www.ncbi.nlm.nih.gov/pubmed/29623076
http://dx.doi.org/10.3389/fimmu.2018.00428

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