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Autoantibodies in Serum of Systemic Scleroderma Patients: Peptide-Based Epitope Mapping Indicates Increased Binding to Cytoplasmic Domains of CXCR3
Systemic sclerosis (SSc) is a severe chronic autoimmune disease with high morbidity and mortality. Sera of patients with SSc contain a large variety of autoantibody (aab) reactivities. Among these are functionally active aab that bind to G protein-coupled receptors (GPCR) such as C-X-C motif chemoki...
Autores principales: | Recke, Andreas, Regensburger, Ann-Katrin, Weigold, Florian, Müller, Antje, Heidecke, Harald, Marschner, Gabriele, Hammers, Christoph M., Ludwig, Ralf J., Riemekasten, Gabriela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874968/ https://www.ncbi.nlm.nih.gov/pubmed/29623076 http://dx.doi.org/10.3389/fimmu.2018.00428 |
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