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The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally
BACKGROUND: Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recruited ge...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875001/ https://www.ncbi.nlm.nih.gov/pubmed/29598828 http://dx.doi.org/10.1186/s13072-018-0184-2 |