The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

BACKGROUND: Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recruited ge...

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Detalles Bibliográficos
Autores principales: García-Molinero, Varinia, García-Martínez, José, Reja, Rohit, Furió-Tarí, Pedro, Antúnez, Oreto, Vinayachandran, Vinesh, Conesa, Ana, Pugh, B. Franklin, Pérez-Ortín, José E., Rodríguez-Navarro, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875001/
https://www.ncbi.nlm.nih.gov/pubmed/29598828
http://dx.doi.org/10.1186/s13072-018-0184-2

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