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The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals

Alpha-1 antitrypsin (AAT) is the most abundant serine protease inhibitor circulating in the blood. AAT deficiency (AATD) is an autosomal codominant condition affecting an estimated 3.4 million individuals worldwide. The clinical disease associated with AATD can present in a number of ways including...

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Detalles Bibliográficos
Autores principales: Dunlea, Danielle M, Fee, Laura T, McEnery, Thomas, McElvaney, Noel G, Reeves, Emer P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875399/
https://www.ncbi.nlm.nih.gov/pubmed/29618937
http://dx.doi.org/10.2147/JIR.S156405