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The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages

Autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a primary immunodeficiency caused by mutations in the autoimmune regulator gene (AIRE). Patients with AIRE mutations are susceptible to Candida albicans infection and present with autoimmune disorders. We previously demonstra...

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Detalles Bibliográficos
Autores principales: de Albuquerque, Jose Antonio Tavares, Banerjee, Pinaki Prosad, Castoldi, Angela, Ma, Royce, Zurro, Nuria Bengala, Ynoue, Leandro Hideki, Arslanian, Christina, Barbosa-Carvalho, Marina Uchoa Wall, Correia-Deur, Joya Emilie de Menezes, Weiler, Fernanda Guimarães, Dias-da-Silva, Magnus Regios, Lazaretti-Castro, Marise, Pedroza, Luis Alberto, Câmara, Niels Olsen Saraiva, Mace, Emily, Orange, Jordan Scott, Condino-Neto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875531/
https://www.ncbi.nlm.nih.gov/pubmed/29666621
http://dx.doi.org/10.3389/fimmu.2018.00567