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Taking the Occam’s Razor Approach to Hedgehog Lipidation and Its Role in Development

All Hedgehog (Hh) proteins signal from producing cells to distant receiving cells despite being synthesized as N-and C-terminally lipidated, membrane-tethered molecules. To explain this paradoxical situation, over the past 15 years, several hypotheses have been postulated that tie directly into this...

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Detalles Bibliográficos
Autores principales: Manikowski, Dominique, Kastl, Philipp, Grobe, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875562/
https://www.ncbi.nlm.nih.gov/pubmed/29615552
http://dx.doi.org/10.3390/jdb6010003