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Taking the Occam’s Razor Approach to Hedgehog Lipidation and Its Role in Development
All Hedgehog (Hh) proteins signal from producing cells to distant receiving cells despite being synthesized as N-and C-terminally lipidated, membrane-tethered molecules. To explain this paradoxical situation, over the past 15 years, several hypotheses have been postulated that tie directly into this...
Autores principales: | Manikowski, Dominique, Kastl, Philipp, Grobe, Kay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875562/ https://www.ncbi.nlm.nih.gov/pubmed/29615552 http://dx.doi.org/10.3390/jdb6010003 |
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